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Trospium Dosing

For most people with an overactive bladder, trospium dosing typically starts at 20 mg twice a day. However, people with kidney disease or who are 75 and older should start with a lower dose, such as 20 mg once daily. To maintain an even level of the medicine in your blood, be sure to take your trospium dosage at the same times each day.

Trospium Dosing: An Introduction

The dose of trospium chloride (Sanctura®) that your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your age
  • Other medications you may be taking
  • How you respond to trospium
  • Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Trospium Dosing for an Overactive Bladder

The recommended starting dose of trospium for overactive bladder treatment is 20 mg twice daily. However, your healthcare provider may recommend a lower dose (trospium 20 mg once daily at bedtime) if you have kidney disease.
If you are age 75 or older, your healthcare provider may consider decreasing your dose to 20 mg once daily, especially if you are experiencing bothersome side effects of trospium. Elderly people are more likely to experience bothersome side effects.

General Information on Dosing With Trospium

Considerations for people taking trospium include the following:
  • The medication comes in tablet form. It is usually taken by mouth twice a day.
  • Trospium should be taken at least one hour before a meal, since it should be taken on an empty stomach.
  • Trospium should be taken at the same times each day to maintain an even level in your blood.
  • For the medication to work properly, it must be taken as prescribed. Trospium will not work if you stop taking it.
  • If you are unsure about anything related to trospium dosing, talk to your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.
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