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Precautions and Warnings With Trospium

Specific Precautions and Warnings With Trospium

Warnings and precautions to be aware of prior to taking trospium include the following:
  • In rare cases, this medication can cause life-threatening swelling of the face, lips, tongue, or throat. This can occur quickly, even after the first dose. Seek immediate medical attention if such swelling occurs.


  • The medication can slow down the digestive system. This can cause problems, especially for people who already have a slow digestive system due to myasthenia gravis, ulcerative colitis, or other problems.
  • This medication may make glaucoma worse. If you have glaucoma and take trospium, your healthcare provider may need to monitor you more closely.
  • The kidneys and liver help to remove trospium from your body. Therefore, if you have kidney or liver disease, you may require extra monitoring by your healthcare provider and may need to take a lower trospium dosage.
  • Trospium can cause blurred vision, dizziness, and drowsiness. Make sure you know how the drug affects you before driving or operating heavy machinery.
  • Trospium can decrease your ability to sweat, which may increase your risk of heat stroke. Be sure to stay well hydrated in the heat.
  • Trospium may potentially interact with a number of other medications (see Drug Interactions With Trospium).
  • Trospium is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known (see Sanctura and Pregnancy).
  • It is not known whether trospium passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Sanctura and Breastfeeding).
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