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What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking tolterodine if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, including liver failure, cirrhosis, or hepatitis
  • An irregular heart rhythm (arrhythmia)
  • Glaucoma
  • Digestive problems (especially those that involve slow emptying of food from the stomach)
  • Difficulty passing urine
  • Myasthenia gravis
  • An enlarged prostate (also known as benign prostatic hyperplasia, or BPH)
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Tolterodine to learn more, including information on who should not take the drug.)

How Does Tolterodine Work?

Tolterodine belongs to a group of medications known as antimuscarinics or anticholinergics. The drug works by blocking specific receptors in the bladder, called muscarinic receptors, which helps to relax the muscles of the bladder. Since an overactive bladder is often due to muscle contractions that are too frequent and uncontrollable, tolterodine can help relieve many of these related symptoms.

Effects of Tolterodine

Studies have shown tolterodine to be effective in relieving many of the symptoms of an overactive bladder. In clinical studies, people who took the drug significantly reduced the frequency of wetting accidents and needed to use the bathroom less frequently.
In addition, people who took tolterodine were able to pass more urine each time they used the bathroom (the frequent muscle contractions of an overactive bladder usually prevent the bladder from holding a normal amount of urine).
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