Drug Interactions With Tolterodine

Acetylcholinesterase inhibitors, certain antifungals or antibiotics, and cyclosporine are some of the medications that may cause drug interactions with tolterodine. To prevent these, tell your healthcare provider about all other medicines you are taking (including non-prescription ones) before starting treatment. Drug interactions with tolterodine could increase your risk of side effects or affect the level of medicine in your blood.

Drug Interactions With Tolterodine: An Overview

Tolterodine tartrate (Detrol®) can potentially interact with a few other medicines. Some of the medicines that may lead to drug interactions with tolterodine include:
 
  • Acetylcholinesterase inhibitor medications, such as:
 
 
  • Anticholinergic drugs, such as:
 
 
  • Certain antifungals or antibiotics, such as:
 
    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Telithromycin (Ketek®)
 
  • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
  • Medications that cause an irregular heart rhythm called QT prolongation (see QT-Prolonging Medications), such as:
 
 
 
 
  • Vinblastine.
     

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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