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Teriparatide

Effects of Teriparatide

This medication has been evaluated in several studies for various osteoporosis-related uses.
 
Teriparatide and Postmenopausal Women
Teriparatide has been evaluated in four studies of postmenopausal women with osteoporosis. In these studies, taking teriparatide (along with calcium and vitamin D) reduced the risk of vertebral fractures (broken spinal bones) by 65 percent, compared to women who took just calcium and vitamin D. Teriparatide also reduced the risk of non-vertebral fractures (broken bones other than the spine) by 53 percent. Also, women taking it showed increased bone mineral density, compared to the women not taking the drug.
 
Teriparatide and Men
Studies have shown that teriparatide can help increase bone mineral density in men with osteoporosis. Studies have not shown that the drug prevents broken bones in men. However, this is most likely due to the small number of men in studies, since studies need many people in order to show any changes in the frequency of broken bones.
 
Teriparatide and Steroid-Induced Osteoporosis
Studies have also shown that teriparatide can increase bone mineral density in both men and women with osteoporosis due to long-term use of glucocorticoid steroids (such as prednisone).
 

When and How to Take It

General considerations for when and how to take teriparatide include the following:
 
  • The medication comes in injectable form. It is injected once daily just under the skin, in the abdomen (lower stomach area) or thigh.
     
  • You can take it with or without food.
     
  • You can take teriparatide at any time of the day, but it is a good idea to take it at the same time each day.
     
  • Your healthcare provider should teach you exactly how to inject teriparatide. Make sure you understand how to give yourself the injections.
     
  • You should be sitting down when you give yourself your first few teriparatide injections in case you get dizzy.
     
  • You should use a new needle for each dose.
     
  • Each teriparatide pen can be used for only 28 days after the first use. You must discard the pen after 28 days, even if there is some drug left in it.
     
  • You need to make sure that you get enough calcium and vitamin D while taking teriparatide, as the medicine cannot build bone without these substances.
     
  • For the medication to work properly, it must be taken as prescribed. It will not work if you stop taking it.
     
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