Synvisc-One Warnings and Precautions
Before you start treatment with Synvisc-One, your healthcare provider needs information on your current medical condition and any drugs you are taking; this will help ensure a safe treatment process. Warnings and precautions for Synvisc-One relate to things like avoiding this product if you have a knee infection and being aware that it may cause problems in people who are allergic to feathers or eggs.
What Should I Tell My Healthcare Provider?You should talk with your healthcare provider prior to receiving your injection of Synvisc-One® (Hylan G-F 20) if you have:
- A swollen leg, ankle, or foot
- Circulatory problems (such as blood clots) in the legs
- An infection in or around the knee
- Any allergies, including to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking about becoming pregnant
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Specific Precautions and Warnings With Synvisc-OneWarnings and precautions to be aware of prior to receiving your injection include the following:
- Your healthcare provider should not inject any medications (such as steroids or anesthetics) into the knee joint along with Synvisc-One, as this would dilute Synvisc-One and make it less effective. It is okay for your healthcare provider to inject a local anesthetic to help numb the area prior to the injection.
- If you are allergic to any bird products, such as feathers or eggs, you might also be allergic to Synvisc-One, since it is made from chicken combs.
- In the United States, Synvisc-One is not approved for injection into any other joint except the knees.
- This product should not be injected into the bloodstream or anywhere else except the knee joint.
- Synvisc-One should be used with caution if you have swelling or circulation problems of the leg, ankle, or foot.
- It is unknown if Synvisc-One passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to receiving your injection (see Synvisc-One and Breastfeeding).
- It is unknown if Synvisc-One is safe for use during pregnancy (see Synvisc-One and Pregnancy).