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Clinical Effects

In studies, treatment with Synvisc-One has been shown to provide superior pain relief, compared with injection of salt water (a "placebo" injection). This benefit has been shown to last as long as six months.

How Is It Injected?

General considerations to keep in mind during treatment with this medication include the following:
  • This product comes in the form of a gel-like liquid that is injected directly into the knee joint. Your healthcare provider will administer the injections.
  • Your knee will be cleansed, and a local anesthetic will usually be injected with a small needle to help prevent pain. A larger needle will then be inserted directly into the knee joint. Your healthcare provider will "drain" fluid from the joint before switching syringes and injecting Synvisc-One.
  • The draining of the joint and the injection of Synvisc-One are done with the same needle, so you will need to be "stuck" with a needle only twice (once for the anesthetic and once for the draining and the Synvisc-One injection). Some healthcare providers may use a topical anesthetic ("numbing cream") instead of an anesthetic injection.
  • The entire procedure is brief and is done in your healthcare provider's office.
  • You can resume most of your usual activities, although your healthcare provider may recommend avoiding strenuous activity for a day or two after the injection.

Dosing Information

There is only one standard recommended dose for this product, although you can choose to have both knees treated at the same time, if necessary.
(Click Synvisc-One Dosage for more information.)
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Synvisc-One Treatment Information

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