Sorine
® (
sotalol hydrochloride) is a prescription medication approved to treat various irregular heart rhythms (arrhythmias). Although other forms of sotalol (such as
Betapace AF
®) are approved to treat
atrial fibrillation and atrial flutter, Sorine is not approved for such uses.
Sorine is made by Upsher Smith Laboratories, Inc. Generic versions are made by several manufacturers.
How Does the Medication Work?
Sorine belongs to two different classes of drugs; it is both a
beta blocker and a Class III antiarrhythmic medication.
As a beta blocker, Sorine slows the heart rate and increases the amount of time that a certain area of the heart (the AV node) is not responsive to an electrical signal. This means that if an electrical signal comes too soon, which could happen with atrial fibrillation or atrial flutter, the signal will not pass on to the rest of the heart.
As a Class III antiarrhythmic medication, Sorine blocks potassium channels in the heart. This action helps to control an irregular heart rhythm.