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Precautions and Warnings With Solifenacin Succinate

Specific Precautions and Warnings With Solifenacin Succinate

Warnings and precautions to be aware of prior to taking solifenacin succinate include the following:
  • In rare cases, solifenacin succinate can cause swelling of the face, lips, tongue, or throat. This may interfere with breathing and can be dangerous. Stop taking solifenacin succinate immediately and seek medical attention if you experience such problems.


  • In studies, high doses of the drug increased the risk of a potentially dangerous irregular heart rhythm called QT prolongation. If you already have an arrhythmia (especially long QT syndrome), solifenacin succinate may make it worse.
  • Solifenacin succinate can slow down the digestive system. This can cause problems, especially for people who already have a slow digestive system due to other medical problems.
  • This medication may make glaucoma worse. If you have glaucoma and take solifenacin succinate, your healthcare provider may need to monitor you more closely.
  • The kidneys and liver help to remove solifenacin succinate from your body. If you have kidney or liver disease, you may require extra monitoring by your healthcare provider and may need to take a lower dosage.
  • Solifenacin succinate can cause blurred vision, dizziness, and drowsiness. Make sure you know how the medicine affects you before driving or operating heavy machinery.
  • The medication can decrease your ability to sweat, which may increase your risk of heat stroke. Be sure to stay well hydrated in the heat.
  • Solifenacin succinate may interact with a number of other medications (see Drug Interactions With Solifenacin Succinate).
  • Solifenacin succinate is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known (see VESIcare and Pregnancy).
  • It is not known whether solifenacin succinate passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see VESIcare and Breastfeeding).
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