Drug Interactions With Solifenacin Succinate

Medicines that may cause drug interactions with solifenacin succinate include pramlintide, protease inhibitors, anticholinergic drugs, and certain antifungals or antibiotics. These interactions can increase the level of solifenacin succinate in your blood, reduce the medications' effectiveness, and increase your risk for side effects. To help prevent drug interactions with solifenacin succinate, talk to your healthcare provider before taking other medicines.

 

Drug Interactions With Solifenacin Succinate: An Overview

Solifenacin succinate (VESIcare®) can potentially interact with several other medicines. Some of the medicines that may lead to solifenacin succinate drug interactions include:
 
  • Acetylcholinesterase inhibitor medications, such as:
 
 
  • Anticholinergic drugs, such as:
 
 
  • Certain antifungals or antibiotics, such as:
 
    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Telithromycin (Ketek®)
 
 
 
 
 
(Drug Interactions With Solifenacin Succinate Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;