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Drug Interactions With the Shingles Vaccine

Shingles Vaccine Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when the shingles vaccine is combined with any of the drugs listed above.


Immune Globulins

Immune globulins may decrease your body's ability to produce an immune response to the shingles vaccine, making the vaccine less effective. Let your healthcare provider know if you receive immune globulin before or after your vaccination, as your vaccination may need to be postponed or, in some cases, repeated.



If you are taking immunosuppressant medications, the shingles vaccine may not work as well as it should. The shingles vaccine works by stimulating your immune system to make antibodies that will fight off the shingles virus. If you are taking medications that suppress and weaken the immune system, your immune system may not be able to make enough antibodies. Also, if your immune system is severely suppressed, it is possible that you may actually get a case of shingles from the vaccine. Make sure to let your healthcare provider know if you have taken or plan to take an immunosuppressant before or after your vaccination.


Other Vaccines

Giving the shingles vaccine at the same time with most other vaccines has not been studied. It is not known whether the shingles vaccine will interact with most other vaccines. However, it can be given at the same time as the flu shot (influenza vaccine) without causing any problems.


Final Thoughts on Shingles Vaccine Drug Interactions

It is possible that not every drug interaction with the shingles vaccine was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the shingles vaccine drug interactions that may apply to you.


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