Drug Interactions With Rivastigmine

Cholinergic drugs, anticholinergic medications, and nonsteroidal anti-inflammatory drugs could potentially cause drug interactions with rivastigmine. These interactions could increase the risk of side effects or decrease the effectiveness of the drugs. To help reduce your risk of developing negative drug interactions with rivastigmine, tell your healthcare provider about all other medications you are taking before starting treatment.

 

Drug Interactions With Rivastigmine: An Overview

Rivastigmine tartrate (Exelon®) can potentially interact with several different medications. Some of the medicines that may lead to drug interactions with rivastigmine include:
 
  • Anticholinergic medications, such as:
 
 
  • Cholinergic drugs (including other acetylcholinesterase inhibitors), such as:
 
    • Ambenonium (Mytelase®)
    • Donepezil (Aricept®)
    • Bethanechol (Urecholine®)
    • Edrophonium (Enlon®, Reversol®)
    • Guanidine
    • Methacholine (Provocholine®)
    • Succinylcholine (Anectine®, Quelicin®)
    • Tacrine (Cognex®)
 
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
 
 
This article refers to the oral forms of rivastigmine (capsules and oral solution). The drug also comes in patch form (see Rivastigmine Patch for more information).
 
(Drug Interactions With Rivastigmine Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;