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Drug Interactions With Risedronate Delayed-Release

Iron Supplements
Iron binds to risedronate delayed-release in the stomach, preventing it from being absorbed in the body and making it less effective. Be sure to wait at least 30 minutes after taking risedronate delayed-release before taking an iron supplement.
 
Magnesium Products
Magnesium binds to risedronate delayed-release in the stomach, preventing it from being absorbed in the body and making it less effective. Be sure to wait at least 30 minutes after taking risedronate delayed-release before taking any magnesium products.
 
Nonsteroidal Anti-Inflammatory Drugs
Both NSAIDs and risedronate delayed-release can be irritating to the stomach. Talk to your healthcare provider before taking these drugs together.
 
Proton Pump Inhibitors (PPIs)
The delayed-release coating on risedronate delayed-release tablets is designed to stay intact in an acidic environment, like the stomach, and to dissolve in a less acidic environment, like the small intestine. By decreasing the acidity of the stomach, PPIs could cause risedronate delayed-release tablets to dissolve too quickly -- in the stomach, instead of the intestines -- perhaps decreasing the absorption of the drug. If you take risedronate delayed-release, check with your healthcare provider before taking a PPI.
 
Teriparatide
In studies, combining teriparatide with medications like risedronate delayed-release seemed to make teriparatide less effective. Talk to your healthcare provider before using these medications together.
 

Final Thoughts

It is possible that not all risedronate delayed-release drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
 
Calcium and Strong Bones

Risedronate Delayed-Release Drug Information

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