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Side Effects of Pramipexole ER

Common Side Effects

Pramipexole ER has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking pramipexole ER were documented and then compared to the side effects that occurred in a similar group of people taking a placebo (a "sugar pill" with no active ingredients) or a short-acting version (pramipexole).
In these studies, the most common, bothersome (but not usually dangerous) pramipexole ER side effects included:
  • Drowsiness -- in up to 36 percent of people
  • Nausea -- up to 22 percent
  • Constipation -- up to 14 percent
  • Dizziness -- up to 12 percent
  • Fatigue -- up to 6 percent
  • Dry mouth -- up to 5 percent
  • Muscle spasms -- up to 5 percent.
Other common side effects (occurring in 1 to 4 percent of people) included:
  • Shakiness (tremors)
  • Headaches
  • Balance problems
  • Vomiting
  • Upper abdominal pain (stomach pain)
  • Indigestion or heartburn
  • General weakness
  • Insomnia
  • Low blood pressure when suddenly standing or sitting up
  • A spinning sensation (vertigo)
  • Increased appetite
  • Coughing.

Final Thoughts

You may experience some or none of the pramipexole ER side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while using this product or if you develop something that "just does not seem right." While it may not be related to pramipexole ER use, your healthcare provider will be able to diagnose and treat the problem.
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