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Pramipexole ER Dosage

For the treatment of Parkinson's disease, the suggested starting dosage of pramipexole ER is 0.375 mg once daily. If necessary, your healthcare provider can increase this amount in gradual increments. The dosage should not be increased more often than once every five to seven days. Do not suddenly stop taking this drug.

An Introduction to Dosing With Pramipexole ER

The dose of pramipexole ER (Mirapex® ER™) that your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • How you respond to pramipexole ER
  • Other medications you are taking
  • Other medical conditions you may have.
     
As is always the case, do not adjust your dosing unless your healthcare provider specifically instructs you to do so.
 

Pramipexole ER Dosage for Parkinson's Disease

The recommended starting pramipexole ER dosage for Parkinson's disease treatment is 0.375 mg once daily. Your healthcare provider may increase your dose gradually, if necessary. The dosage should not be increased more often than once every five to seven days. If you stop taking pramipexole ER for more than a few days, you may have to start back at a lower dose (ask your healthcare provider for more information).
 
If you are switching from short-acting pramipexole, you can switch directly to the same daily dose. For instance, if you were taking pramipexole 1.5 mg three times daily (a total daily dose of 4.5 mg), you can switch overnight to pramipexole ER 4.5 mg once daily.
 
When stopping pramipexole ER, it is usually best to reduce the dose gradually over one week.
 
People with kidney disease may need to take a lower or less-frequent-than-normal pramipexole ER dosage. In some cases, an every-other-day dosage of pramipexole ER may be recommended.
 
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Pramipexole ER Drug Information

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