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Drug Interactions With Pramipexole ER

Alcohol
You should avoid alcohol while taking pramipexole ER. Combining the two can increase the risk of falling asleep during the day without warning, which can be serious, especially if you are driving or operating heavy machinery.
 
Antipsychotics
Antipsychotic medications can make pramipexole ER less effective. Check with your healthcare provider before taking these medications together.
 
Cimetidine (Tagamet)
Cimetidine can affect the way your kidneys remove pramipexole ER from the body, possibly increasing the levels of pramipexole ER in your blood and increasing your risk of pramipexole ER side effects. Do not use these medications together without your healthcare provider's approval and supervision.
 
Diltiazem
Diltiazem can affect the way your kidneys remove pramipexole ER from the body, possibly increasing the levels of pramipexole ER in your blood and increasing your risk of pramipexole ER side effects. Do not use these medications together without your healthcare provider's approval and supervision.
 
Medications That Contain Levodopa
Levodopa is one of the most commonly used medications for treating Parkinson's disease. Many people who take pramipexole ER with levodopa will need a lower dosage of levodopa, especially if levodopa side effects develop or become worse. Make sure your healthcare provider takes this into consideration.
 
Metoclopramide
Metoclopramide can make pramipexole ER less effective. Check with your healthcare provider before taking these medications together.
 
Pramipexole
Do not take pramipexole ER and short-acting pramipexole together, as these medications have the same active ingredient.
5 Questions to Ask Your Doctor About ED

Pramipexole ER Drug Information

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