Oxybutynin Drug Interactions

A number of medicines may cause oxybutynin drug interactions, including protease inhibitors, certain antifungals or antibiotics, and anticholinergic medications. Some interactions can make the medications less effective, while others can increase the level of oxybutynin in your blood (which also increases your risk of side effects). To help prevent oxybutynin drug interactions, tell your healthcare provider about all medicines you are taking.

 

An Overview of Oxybutynin Drug Interactions

Oxybutynin chloride (Ditropan®) can potentially interact with several other medications. Some of the medicines that may lead to oxybutynin drug interactions include:
 
  • Acetylcholinesterase inhibitor drugs, such as:
 
 
  • Anticholinergic medications, such as:
 
 
  • Certain antifungal or antibiotic medications, such as:
 
    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Telithromycin (Ketek®)
 
 
 
(Oxybutynin Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;