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Precautions and Warnings With Oxybutynin ER

Specific Warnings and Precautions for Oxybutynin ER

Warnings and precautions to be aware of prior to taking oxybutynin ER include the following:
  • The kidneys and liver help to remove oxybutynin ER from your body. If you have kidney or liver disease, you may require extra monitoring by your healthcare provider and you may need to take a lower oxybutynin ER dosage.
  • Make sure your healthcare provider knows if you have myasthenia gravis, as oxybutynin ER can possibly make myasthenia gravis symptoms worse.
  • Oxybutynin ER can slow your digestive tract. This can be a problem, especially if you already have a slow digestive tract due to other medical conditions.
  • The outer shells of oxybutynin ER tablets do not dissolve. You may see them in your stools, but this is not a problem. However, if you have a narrowing (a stricture) anywhere in your digestive tract, oxybutynin ER tablets could become stuck, since they do not dissolve.


  • In rare cases, oxybutynin ER can cause very serious reactions involving swelling of the tongue or throat. If you begin to experience these symptoms, or if you experience wheezing or difficulty breathing, seek emergency medical attention. 


  • Oxybutynin ER can cause blurred vision, dizziness, and drowsiness. Be sure to see how the medication affects you before you drive or operate heavy machinery.
  • Oxybutynin ER may potentially interact with a number of other medications (see Drug Interactions With Oxybutynin ER).
  • Oxybutynin ER is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not known (see Ditropan XL and Pregnancy).
  • It is not known if oxybutynin ER passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Ditropan XL and Breastfeeding).
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