Drug Interactions With Oxybutynin ER

Certain medications may cause negative drug interactions with oxybutynin ER, including protease inhibitors, other anticholinergics, and some types of antifungals or antibiotics. These interactions can reduce the effectiveness of the medicines, increase the level of oxybutynin ER in your blood, or increase your risk of side effects. To minimize your risk of developing oxybutynin ER interactions, talk to your healthcare provider before taking other medications.

 

An Overview of Oxybutynin ER Drug Interactions

Oxybutynin ER (Ditropan XL®) can potentially interact with a few other medicines. Some of these medicines that may lead to oxybutynin ER interactions include:
 
  • Acetylcholinesterase inhibitor drugs, such as:

 

 

  • Anticholinergic medications, including:

 

 

  • Certain antifungal or antibiotic medications, including:

 

    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Telithromycin (Ketek®)

 

 

 

(Drug Interactions With Oxybutynin ER Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;