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Nitroglycerin Dosage

IV Nitroglycerin Dosing Guidelines

The intravenous (IV) form of nitroglycerin is administered in a hospital setting by your healthcare provider. The dose will be adjusted based on how you respond to the medication. To carefully control the rate at which nitroglycerin is given, this drug should be administered with a pump rather than a standard IV bag.

Off-Label Doses of Nitroglycerin

Nitroglycerin products are sometimes used "off-label" for purposes other than the ones for which they are approved. For instance, nitroglycerin ointment is often used off-label to treat anal fissures. By definition, there are no official dosing recommendations for off-label uses.

General Information on Using Nitroglycerin

Some considerations to keep in mind during treatment with nitroglycerin include the following:
  • This medication comes in several different forms. Refer to your healthcare provider's specific directions for your particular product and situation.
  • The long-acting forms (patches, ointment, and capsules) are used to prevent chest pain and are taken on a daily basis. The short-acting forms (tablets and spray) are used as needed to relieve chest pain.
  • For the short-acting forms (tablet or spray), you can use up to three doses within 15 minutes. If chest pain continues after a third dose, you should seek immediate medical attention, as you may be having a heart attack.
  • For nitroglycerin ointment or patches, carefully read the directions included with your particular product. If you have any questions, talk to your healthcare provider or pharmacist.


  • As you might imagine, the instructions for using nitroglycerin anal ointment (for anal fissures) are quite a bit different than the instructions for other nitroglycerin products (see Rectiv Dosage for more information)
  • If you are unsure about anything related to dosing with nitroglycerin, please talk to your healthcare provider or pharmacist.
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