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Drug Interactions With the Nitroglycerin Patch

When certain medications are taken in combination with the nitroglycerin patch, there is a possibility for negative drug interactions. Some of these reactions can make the medications less effective or increase your risk for complications, such as low blood pressure. Alcohol, calcium channel blockers, and ergot medications are among the substances that can react with the nitroglycerin patch.

An Overview of Nitroglycerin Patch Interactions

Nitroglycerin patches (Minitran™, Nitro-Dur®) may react with a number of other medications. Some of the drugs that can lead to interactions with nitroglycerin patches include but are not limited to:
  • Ergot medications, such as:
    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®)
  • Phosphodiesterase type-5 (PDE5) inhibitors, such as:


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Nitroglycerin Patch Information

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