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Naproxen/Esomeprazole Magnesium Dosage

Your healthcare provider will determine your naproxen/esomeprazole magnesium dosage based on how you respond to the medication. This prescription medication comes in the form of extended-release tablets and is generally taken twice a day. Take each tablet 30 minutes before a meal. Also, swallow the tablet whole; do not crush, cut, or chew it, as it may disrupt the extended-release properties of the drug.

An Introduction to Your Dosage of Naproxen/Esomeprazole Magnesium

The dose of naproxen/esomeprazole magnesium (Vimovo™) your healthcare provider recommends may vary, depending on how you respond to the medication (or how you have responded to similar medications in the past). As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.

Basic Naproxen/Esomeprazole Magnesium Dosing Guidelines

The standard recommended dose of naproxen/esomeprazole magnesium for treating osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis is one tablet (of either strength) twice daily. This medication comes in the following two strengths:
  • Naproxen/esomeprazole magnesium 375/20 mg -- 375 mg of naproxen and 20 mg of esomeprazole
  • Naproxen/esomeprazole magnesium 500/20 mg -- 500 mg of naproxen and 20 mg of esomeprazole.
Therefore, the standard dosages of one tablet of either strength twice daily provides 20 mg of esomeprazole twice daily and either 375 mg or 500 mg of naproxen twice daily. Because the tablets cannot be cut, there is no way to achieve a different dose of esomeprazole (with either strength). If a person needs a different strength of esomeprazole, this product cannot be used.

General Information on Taking Naproxen/Esomeprazole Magnesium

Some considerations to keep in mind while taking naproxen/esomeprazole magnesium include the following:
  • Naproxen/esomeprazole magnesium comes in the form of extended-release tablets and is usually taken by mouth twice daily.
  • Take this medication at least 30 minutes before meals.
  • Do not crush, chew, break, or dissolve the tablets, as this destroys the extended-release properties.
  • For the medication to work properly, it must be taken as prescribed.
  • If you are unsure about anything related to your dosage, please talk with your healthcare provider or pharmacist.
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Naproxen/Esomeprazole Magnesium Drug Information

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