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Drug Interactions With Naproxen/Esomeprazole Magnesium

Certain diuretics, antifungals, iron supplements, and various other drugs can cause negative interactions with naproxen/esomeprazole magnesium. Some of these reactions can change the way your body metabolizes the medications, possibly decreasing the effectiveness of the drugs or increasing your risk for serious side effects. To help minimize risks, make sure your healthcare provider is aware of any other medicines or supplements you are taking.

An Overview of Naproxen/Esomeprazole Magnesium Interactions

Naproxen/esomeprazole magnesium (Vimovo™) is a prescription medication licensed to treat osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. This product may potentially interact with many other medications.
Some of the medications that may lead to naproxen/esomeprazole magnesium drug interactions include but are not limited to:
  • Angiotensin-converting enzyme inhibitors (ACE inhibitors), such as:
  • Certain antifungals, such as:
    • Fluconazole (Diflucan®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Posaconazole (Noxafil®)
    • Voriconazole (VFEND®)
  • Certain diuretics, such as:
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
  • Some protease inhibitors, such as:
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Naproxen/Esomeprazole Magnesium Drug Information

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