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What Is Mycophenolate Sodium Used For?

How Does Mycophenolate Sodium Work?

Mycophenolate sodium works by blocking the action of an enzyme in the body known as inosine monophosphate dehydrogenase (IMPDH). This enzyme is needed for T- and B-lymphocytes (cells that are part of the immune system) to multiply.
Transplant rejection occurs when the immune system, which is responsible for fighting infections, sees the transplanted organ as foreign material and attacks it. By preventing T- and B-lymphocytes from multiplying, mycophenolate sodium decreases the activity of the immune system, which decreases the chance that transplant rejection will occur.

Can Children Use It?

Mycophenolate sodium is approved for use in children who are at least five years old and are stable after a kidney transplant. It has not been adequately studied in children younger than five.
Talk with your child's healthcare provider about the particular benefits and risks of using mycophenolate sodium in children. The tablets cannot be crushed, broken, or chewed. Children who take this medication must be able to swallow the tablet whole.

Can Older Adults Use It?

Older adults can use mycophenolate sodium. In general, older adults may have a higher risk for certain side effects, such as infection, buildup of fluid in the lungs (pulmonary edema), and gastrointestinal (GI) bleeding. Therefore, older adults should be closely monitored to see how they respond to the medication.

Off-Label Mycophenolate Sodium Uses

On occasion, your healthcare provider may recommend this product for something other than the uses discussed in this article. Some possible off-label uses of mycophenolate sodium include:
  • Preventing rejection after a heart or liver transplant
  • Treating idiopathic thrombocytopenic purpura (a disorder that causes abnormal clotting of the blood)
  • Treating lupus nephritis (kidney inflammation caused by systemic lupus erythematosus [SLE])
  • Treating kidney disease
  • Treating atopic dermatitis
  • Treating myasthenia gravis (an autoimmune neuromuscular disorder).
The Dirty, Messy Part of BPH

Mycophenolate Sodium Drug Information

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