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Mycophenolate Sodium Side Effects

Common Side Effects

Mycophenolate sodium has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking mycophenolate sodium were documented and then compared to those that occurred in a similar group of people taking another anti-rejection medicine. As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group taking the other medicine.
In these studies, common side effects of mycophenolate sodium included:
  • Constipation -- in up to 38 percent of people
  • Nausea -- up to 29.1 percent
  • Urinary tract infection (UTI) -- up to 29.1 percent
  • Pain after the transplant surgery -- up to 23.9 percent
  • Diarrhea -- up to 23.5 percent
  • Insomnia -- up to 23.5 percent
  • Vomiting -- up to 23 percent
  • Heartburn or indigestion -- up to 22.5 percent
  • Anemia -- up to 21.6 percent
  • Cytomegalovirus (CMV) infection (a potentially life-threatening viral infection) -- up to 20.2 percent
  • Decreased white blood cell counts (leukopenia) -- up to 19.2 percent.
Other common reactions, occurring in 3 to 20 percent of people, included but were not limited to:
  • Back pain
  • Muscle and joint pain
  • Lack of energy and weakness
  • Abdominal pain (stomach pain)
  • General pain
  • Fever
  • Gas
  • Bloating
  • Tremor
  • Headache
  • Blurred vision
  • Acne
  • Itching
  • Decrease in platelets
  • High blood pressure (hypertension)
  • Cysts
  • Excessive, coarse, dark hair growth
  • Fat deposits on the face and back, causing a round face and a fatty hump on the back of the neck
  • Overgrowth of gum tissue
  • Increased cholesterol (fats or lipids)
  • Increased blood glucose (blood sugar)
  • Changes in blood electrolytes, such as low or high potassium and low calcium, and magnesium
  • Dehydration
  • Pain while urinating, difficulty urinating, and blood in the urine
  • Weight gain
  • Cough
  • Shortness of breath
  • Decreased blood pressure
  • Abnormal kidney function
  • Abnormal liver function tests
  • Dizziness
  • Anxiety
  • Depression
  • Edema (swelling of body tissues, especially of the legs, ankles, and feet)
  • Fast heart rate (tachycardia)
  • Sore throat
  • Upper respiratory tract infection, such as the common cold
  • Pneumonia
  • Cold sores
  • Shingles
  • Sinus congestion
  • Thrush (a fungal infection of the mouth)
  • Wound infection
  • Chest pain
  • Rash
  • Bruises.
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Mycophenolate Sodium Drug Information

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