Miacalcin Injection

Miacalcin injection is used for treating various conditions, including Paget's disease, osteoporosis in postmenopausal women, and high blood calcium. It is a synthetic version of a naturally occurring hormone that helps regulate bone formation and breakdown. Miacalcin injection, which is available by prescription, can be given just under the skin or into the muscle. Potential side effects include nausea, vomiting, and flushing.

What Is Miacalcin Injection?

Miacalcin® injection (calcitonin salmon injection) is a prescription medication approved to treat the following conditions:
 
  • Paget's disease of the bone
  • High blood calcium (hypercalcemia)
  • Osteoporosis in postmenopausal women.
     
(Click Miacalcin Injection Uses for more information, including possible off-label uses.)
 

Who Makes Miacalcin Injection?

Miacalcin injection is made by Novartis Pharmaceuticals.
 

How Does Miacalcin Injection Work?

Miacalcin injection is a manufactured version of calcitonin, a naturally occurring hormone that helps regulate bone formation and breakdown. Miacalcin is actually a synthetic version of calcitonin from salmon (known as calcitonin salmon), which is more potent and longer-acting than human calcitonin. Miacalcin works by slowing down the breakdown of bone. It also appears to have some activity as a pain reliever, independent of its effects on bone.
 
Miacalcin works to decrease blood calcium in several ways. First, as mentioned, it slows the breakdown of bone, which decreases the release of calcium from bone. Second, it increases the ability of the kidneys to excrete calcium into the urine (which helps clear calcium from the blood).
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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