Miacalcin Injection Uses (Cont.)

Miacalcin Injection Uses for Paget's Disease

Normally, bone is continuously being broken down and rebuilt. Paget's disease of the bone is a condition involving rapid breakdown of bone combined with abnormal reformation. The abnormally reformed bone is weaker than normal. Symptoms of Paget's disease can include pain and bent or broken bones. Miacalcin injection can help slow down the rate at which bone breaks down and can help the body build bone more normally.
 
Not all people with Paget's need to be treated with medications. Miacalcin injection is recommended for people who have moderate to severe Paget's disease.
 

Miacalcin Injection Uses for Hypercalcemia

High blood calcium is known medically as hypercalcemia. Calcium is an important mineral and is important for muscle and heart function. High blood calcium can cause the following symptoms:
 
  • Nausea and vomiting
  • Confusion
  • Constipation
  • Lethargy
  • Muscle pain or weakness
  • Increased urination
  • Headaches
  • Changes in the heart rhythm (arrhythmia)
  • Coma.
     
Hypercalcemia can occur due to various causes, such as cancer or hyperparathyroidism. Miacalcin injection is approved for the early treatment of hypercalcemic emergencies (dangerously high blood calcium levels), when there is a need to rapidly decrease the calcium levels. It can be used along with other treatments.
 

How Does Miacalcin Injection Work?

Miacalcin injection is a manufactured version of calcitonin from salmon (known as calcitonin salmon), which is more potent and longer-acting than human calcitonin. As mentioned, it works by slowing down the breakdown of bone. The medicine also appears to have some activity as a pain reliever, independent of its effects on bone.
 
(Miacalcin Injection Uses Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;