Senior Health Home > Drug Interactions With Memantine XR

A number of medications may cause drug interactions with memantine XR, including amantadine, dextromethorphan, and carbonic anhydrase inhibitors, to name a few. Some of these negative reactions can cause high levels of memantine XR in the blood. To help prevent complications, tell your healthcare provider about all other medications you are taking before starting Alzheimer's treatment.

An Overview of Memantine XR Interactions

Memantine XR (Namenda XR®) can potentially interact with a number of other medications. Some of the drugs that may lead to interactions with memantine XR include but are not limited to:

More Information on Drug Interactions With Memantine XR

The following sections explain in detail the potentially negative interactions that can occur when memantine XR is combined with any of the drugs listed above.
Amantadine (Symmetrel)
Amantadine and memantine XR affect certain brain receptors in a similar way. It is not known if it is safe to take these medications together. Make sure to check with your healthcare provider before combining these products.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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