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People who have a skin condition called seborrhea may consider ketoconazole gel. This prescription gel is applied on the skin once daily for two weeks. Although most people tolerate it well, the most commonly reported side effect is a burning sensation at the application site. This medicine is thought to work by killing fungus.

What Is Ketoconazole Gel?

Ketoconazole gel (Xolegel®) is a prescription skin medication. It is approved to treat seborrhea. It is applied just once a day for two weeks.
(Click What Is Ketoconazole Gel Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, ketoconazole gel may cause side effects. However, not everyone who uses the product will experience problems. In fact, most people tolerate it quite well. Serious side effects are less common.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
The most commonly reported side effect of ketoconazole gel is a burning sensation at the application site.
(Click Ketoconazole Gel Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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