Senior Health Home > Drug Interactions With Desonide Ointment

Although negative interactions are not likely to occur when desonide ointment is used with most drugs, there are some medications you may not be able to take while using this ointment. Before starting treatment with this skin medicine, make sure your healthcare provider knows if you are taking aldesleukin or corticorelin. Desonide ointment can decrease the effectiveness of these medications or lead to other problems.

An Overview of Desonide Ointment Interactions

Desonide ointment (DesOwen®) is generally unlikely to interact with other medications. However, there are a few potential drug interactions that may occur. Some of the drugs that can lead to reactions with desonide ointment include but are not limited to:
 
 

Drug Interactions With Desonide Ointment Explained

The following sections explain in detail the potentially negative reactions that can occur when desonide ointment is combined with any of the drugs listed above.
 
Aldesleukin
Corticosteroids, including desonide ointment, can make aldesleukin (a chemotherapy medication) less effective. In general, these medications should not be used together.
 
Corticorelin
Corticosteroids, including desonide ointment, can make corticorelin less effective. Corticorelin is used as a diagnostic agent in tests for Cushing's syndrome or other similar problems. If you are being tested for Cushing's disease, make sure your healthcare provider knows you have been using desonide ointment.
 

Final Thoughts

It is possible that not all drug interactions were discussed in this article. Therefore, before using desonide ointment, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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