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A healthcare provider may prescribe desonide ointment to treat various skin conditions, such as eczema, psoriasis, and dermatitis. This medicine works by suppressing an overactive immune system and reducing inflammation. It is applied directly on the affected areas of the skin two to three times daily. Some potential side effects may include stinging, burning, and skin irritation.

What Is Desonide Ointment?

Desonide ointment (DesOwen®) is a prescription skin medication that comes in the form of an ointment. It belongs to a group of medications known as topical steroids and is used to treat inflammation and itching due to a wide variety of skin conditions, such as eczema, psoriasis, dermatitis, and allergic reactions.
(Click What Is Desonide Ointment Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, desonide ointment may cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common side effects of desonide ointment include but are not limited to:
  • Stinging and burning
  • Irritation
  • Contact dermatitis (an itchy red rash caused by direct contact with an irritating substance).
(Click Desonide Ointment Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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