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If you have low testosterone levels, your healthcare provider may prescribe Depo-Testosterone. Using this medicine can help increase testosterone levels, whether they are due to a problem in the brain or in the testes. In some cases, a healthcare provider may recommend using this drug off-label to treat low testosterone in women or as a hormone therapy in transgender individuals.

What Is Depo-Testosterone Used For?

Depo®-Testosterone (testosterone cypionate) is a prescription testosterone replacement medication. It is approved for treating certain causes of low testosterone in men.
Common symptoms of low testosterone include:
  • Low sex drive (libido)
  • Fatigue and low energy
  • Decreased muscle mass and increased fat mass
  • Problems with erectile function
  • Decreased bone strength
  • Depression.
Of course, a man could have all of these symptoms and still have normal testosterone levels, as most of these symptoms are relatively common. The only real way to diagnose low testosterone is by actually measuring testosterone levels in the blood. Treating low testosterone levels with Depo-Testosterone (or any other testosterone replacement therapy) based on symptoms alone (without testing testosterone levels) is highly inappropriate and potentially dangerous.
There are several different causes of low testosterone in men. Normally, testosterone is produced when the testes are stimulated by certain hormone signals from glands in the brain. Low testosterone can occur due to problems in the brain or the testes.
Regardless of whether the problem lies in the testes or the brain, Depo-Testosterone can increase testosterone levels because it does not rely on either the testes or the brain to work.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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