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General Information on Dosing With Carbidopa-Levodopa CR

Some considerations for people taking carbidopa-levodopa CR include the following:
  • The medication comes in extended-release tablet form. It is taken by mouth usually two or three times a day.
  • Do not crush or chew carbidopa-levodopa CR tablets. However, carbidopa-levodopa CR 50-200 mg tablets (but not 25-100 mg tablets) may be broken in half along the score line if necessary.
  • The protein in food can decrease the absorption of carbidopa-levodopa CR into the body. Some healthcare providers recommend taking carbidopa-levodopa CR on an empty stomach (or with a low-protein diet).
  • Make sure to take carbidopa-levodopa CR at the same times each day to maintain an even level of the medication in your blood.
  • For the medication to work properly, it must be taken as prescribed. Carbidopa-levodopa CR will not work if you stop taking it. Do not suddenly stop taking the drug without first talking to your healthcare provider.
  • If you are unsure about anything related to your carbidopa-levodopa CR dosage, please talk with your doctor, nurse, or pharmacist.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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