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When and How to Use This Medicine

Some general considerations to keep in mind during treatment with aflibercept include the following:
  • Aflibercept is injected into the eye.
  • For age-related macular degeneration, it is injected monthly for the first 12 weeks, and then once every two months thereafter.
  • For macular edema caused by retinal vein occlusion, it is injection once a month.
  • Your eye(s) will be cleansed to prevent infection, and your eye(s) will be numbed before the injection. While you should feel no pain, you may feel a little pressure.
  • For aflibercept to work properly, it must be used as prescribed.

Storage Information

Your healthcare provider should store aflibercept under refrigeration.

Is There a Generic Version?

This medication is not available in generic form (see Generic Eylea).

Who Makes Aflibercept?

Aflibercept is made by Regeneron Pharmaceuticals, Inc.

Available Strengths

Each vial contains 0.285 mL of aflibercept, with a concentration of 40 mg per mL. This amount is just enough for one 0.05-mL dose of the medication; it is impossible to remove every last drop of a medication in a vial, so there is always some overfill.
If you need treatment in both eyes, you will need one vial for each eye; the same vial cannot be used for two eyes.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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