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Locoid Lipocream Warnings and Precautions

People with certain allergies may not be able to safely use Locoid Lipocream. Other precautions and warnings with this drug apply to women who are pregnant or breastfeeding. In addition, it is important to follow your healthcare provider's dosing instructions carefully, as using too much of this drug for long periods can cause problems like Cushing's syndrome or diabetes.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Locoid Lipocream® (hydrocortisone butyrate) if you:
  • Are breastfeeding
  • Are pregnant or thinking of becoming pregnant
  • Have any allergies, including to food, dyes, or preservatives.
You should also be sure to tell your healthcare provider about all of the medicines you take, including prescription and nonprescription medications, vitamins, and herbal supplements.

Specific Precautions and Warnings With Locoid Lipocream

Some warnings and precautions to be aware of with this medication include:
  • Locoid Lipocream is a steroid and, as such, can cause serious side effects. While it is not a particularly potent steroid, using too much or using it too long increases the risk of serious side effects.
  • Steroids can cause serious side effects, such as Cushing's syndrome or diabetes. Although this is more likely to occur with oral or injected steroids, it is still possible with topical steroids, such as Locoid Lipocream. The more you apply and the longer you use the drug, the more likely these problems are to occur. Covering the cream with a dressing -- which is not recommended -- may also increase the risk.
  • If you use this medication for an extended period, be sure to watch for any signs of Cushing's syndrome (a group of symptoms caused by prolonged exposure to steroids), such as:
    • A rounded face
    • Unusual body fat distribution (more fat in the trunk, face, and neck, and less fat in the arms and legs)
    • High blood sugar.
Let your healthcare provider know if you think you have signs of this problem.
  • Locoid Lipocream can suppress the body's ability to make natural steroids. Usually, this happens when large doses are used over a long period, which is not recommended. In such circumstances, this medicine should be stopped slowly to give your body a chance to begin making natural steroids again. If this is not feasible, you might need to be given an oral steroid for a while, after which you will be slowly weaned from it.
  • Like all steroids, Locoid Lipocream may slow down the growth rate of children and teenagers. Contact your child's healthcare provider if you are concerned about this. In general, children may be more susceptible to side effects of steroids. Close monitoring is necessary for any child receiving long-term steroids.
  • If you develop a skin infection while using Locoid Lipocream, you will need to be treated with appropriate antibiotics or antifungal medications. If the infection does not clear up, you may need to stop using this medicine.
  • Locoid Lipocream can potentially react with a few other medications (see Locoid Lipocream Drug Interactions).
  • This product is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not currently known (see Locoid Lipocream and Pregnancy).
  • It is unknown if Locoid Lipocream passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the drug (see Locoid Lipocream and Breastfeeding).
The Dirty, Messy Part of BPH

Locoid Lipocream Information

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