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What Is Ibuprofen/Famotidine Used For?

A healthcare provider may prescribe ibuprofen/famotidine for treating osteoarthritis or rheumatoid arthritis in adults. In addition to ibuprofen, this combination drug also contains famotidine, which helps to prevent stomach ulcers that may develop due to the ibuprofen. Sometimes, ibuprofen/famotidine may be used "off-label" to treat several conditions, such as other types of pain and inflammation.

An Overview of Ibuprofen/Famotidine Uses

Ibuprofen/famotidine (Duexis™) is a prescription medication that combines a nonsteroidal anti-inflammatory drug (ibuprofen) with an acid reducer medication (famotidine) to help decrease the risk of stomach and intestinal ulcers caused by ibuprofen. It is approved to treat the following conditions:

Using Ibuprofen/Famotidine for Osteoarthritis

Ibuprofen/famotidine is approved for treating osteoarthritis, which is the most common type of arthritis. This painful condition occurs when cartilage -- the tissue that pads bones in a joint -- begins to become ragged and wears away. Over time, all of the cartilage in a joint can wear away, leaving bones that rub against each other. In addition, the fluid within the joint that normally lubricates and cushions the joints becomes thin and less able to protect the joint, contributing to the development of osteoarthritis symptoms.
Osteoarthritis research scientists do not know the exact cause or causes of osteoarthritis, although aging plays an important role.
While there is no cure for osteoarthritis, there are treatments that can ease pain and improve function.
Some specific treatments include:
Nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, are often quite effective for treating osteoarthritis, although they can cause significant side effects, including ulcers. Ibuprofen/famotidine combines ibuprofen with famotidine to help reduce the risk for ulcers.
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Ibuprofen/Famotidine Drug Information

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