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What Is Ibuprofen/Famotidine Used For?

Using Ibuprofen/Famotidine for Rheumatoid Arthritis

Ibuprofen/famotidine is also approved for the treatment of rheumatoid arthritis, a type of autoimmune disease. This means that for some reason the immune system mistakes a person's own cells as invaders and attacks them, causing damage. Similar to other autoimmune diseases, the cause or causes of rheumatoid arthritis are still unknown. There are many rheumatoid arthritis symptoms, including chronic pain along with tender, warm, and swollen joints.

How Does It Work?

Ibuprofen/famotidine contains two different active ingredients: ibuprofen and famotidine. Ibuprofen belongs to a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). Like other NSAIDs, it works by blocking a specific enzyme known as cyclooxygenase (COX), blocking the production of various inflammatory substances in the body.
The other active ingredient (famotidine) is an H2 blocker that works by blocking a specific kind of histamine receptor. Histamine is a chemical released by the body that has several effects. In the stomach, histamine causes more acid to be produced. By blocking histamine in the stomach, famotidine reduces the amount of acid produced by the stomach. This is why famotidine is known as an "acid reducer" or "acid controller."
Ibuprofen is quite effective, but many people cannot take it because it has a tendency to cause ulcers. Famotidine is added in order to help reduce the risk of ulcers.

Can Children Use Ibuprofen/Famotidine?

Ibuprofen/famotidine is not approved for use in children. Talk with your child's healthcare provider about the benefits and risks of using this medicine in children.

Are There Off-Label Uses?

On occasion, your healthcare provider may recommend this medicine for something other than the approved uses discussed in this article. This is called an "off-label" use. At this time, using ibuprofen/famotidine to treat any other type of pain or inflammation would be considered an off-label use. For instance, using ibuprofen/famotidine for treating chronic back pain that is not caused by osteoarthritis would be an off-label use.
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Ibuprofen/Famotidine Drug Information

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