Ibuprofen/Famotidine Side Effects
Common Side EffectsIbuprofen/famotidine has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking ibuprofen/famotidine were documented and compared to side effects that occur in another group of people taking just ibuprofen. As a result, it was possible to see what ibuprofen/famotidine side effects occurred, how often they appeared, and how they compared to ibuprofen alone.
In these studies, the most common ibuprofen/famotidine side effects included:
- Nausea -- in up to 6 percent of people
- Indigestion or heartburn -- up to 5 percent
- Diarrhea -- up to 5 percent
- Constipation -- up to 4 percent
- Upper respiratory tract infections, such as the common cold -- up to 4 percent
- Upper abdominal (stomach) pain -- up to 3 percent
- Headaches -- up to 3 percent
- High blood pressure (hypertension) -- up to 3 percent.
Other common side effects, occurring in 1 to 2 percent of people, included but were not limited to:
- Gastroesophageal reflux disease (GERD)
- Abdominal (stomach) discomfort
- Abdominal (stomach) pain
- Swelling/water retention in the hands, lower legs, or feet
- Sinus infections
- Stuffy or runny nose
- A sore throat
- Urinary tract infection (UTI), such as a bladder infection
- The flu
- Joint pain
- Back pain
- Throat pain.
It is possible that many of these reported side effects may not be real side effects at all, as the studies did not compare ibuprofen/famotidine to a placebo (a medicine that does not contain any active ingredients). For instance, 3 percent of people given ibuprofen/famotidine, as well as 3 percent of the people taking ibuprofen only, had a headache. Because there is no placebo to compare it to, it is possible that the headaches were completely unrelated to the medication.