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Drug Interactions With Ibuprofen/Famotidine

More Detail on Drug Interactions With Ibuprofen/Famotidine

The following sections explain in detail the potentially negative reactions that can occur when ibuprofen/famotidine is combined with any of the drugs listed above.
 
ACE Inhibitors
Ibuprofen/famotidine can make ACE inhibitors less effective at lowering blood pressure and may also increase the risk for kidney damage. If you take ibuprofen/famotidine with an ACE inhibitor, your healthcare provider should monitor your blood pressure and your kidney function to watch for this interaction.
 
Certain Diuretics
Ibuprofen/famotidine may decrease the effectiveness of many diuretics. In addition, combining ibuprofen/famotidine with a diuretic may increase the risk for kidney damage. If you take such medications together, your healthcare provider should monitor your kidney function and make sure that your diuretic is still working effectively.
 
Lithium
Combining lithium with ibuprofen/famotidine may increase the level of lithium in the blood, perhaps causing lithium toxicity. If you take ibuprofen/famotidine with lithium, your healthcare provider should monitor you closely to watch for this interaction.
 
Methotrexate
Ibuprofen/famotidine might increase the risk for methotrexate side effects. Check with your healthcare provider before combining these two medications.
 
"Blood Thinners"
Combining ibuprofen/famotidine with other medications that have anticoagulant, thrombolytic, or antiplatelet activity might increase the risk for bleeding, including dangerous internal bleeding. Check with your healthcare provider before taking ibuprofen/famotidine with any such medications, even nonprescription ones.
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Ibuprofen/Famotidine Drug Information

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