Senior Health Channel
Topics & Medications
Related Channels

Side Effects of Hylan G-F 20

Possible Side Effects of Hylan G-F 20

Hylan G-F 20 has been studied thoroughly in clinical trials in which people were randomly treated with either hylan G-F 20 or a placebo (in this case, a saline injection). This way, researchers were able to distinguish between side effects of the drug and side effects caused just by injecting a substance into the joint.
The most common side effects of the Synvisc-One formulation of hylan G-F 20 included:
  • Knee pain -- in up to 25.2 percent of people
  • Knee stiffness -- up to 8.1 percent
  • Fluid buildup around the knee -- up to 5.7 percent
  • Knee swelling -- up to 4.1 percent
  • Knee warmth -- up to 1.6 percent.
Other possible side effects seen with Synvisc-One included:
  • Changes in walking gait
  • Muscle pain or muscle cramps
  • Flushing of the face
  • A rapid heart rate (tachycardia)
  • Nausea
  • Dizziness
  • Fever and/or chills
  • Headaches
  • Unusual sensations on the skin, such as tingling or pricking
  • Low blood platelets
  • Ankle swelling
  • Hemorrhoids
  • Lower back pain.

Final Thoughts

You may experience some or none of the hylan G-F 20 side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, make sure to let your healthcare provider know if you develop any side effects during treatment, or if something "just does not seem right." While it may not be a side effect, your healthcare provider will be able to diagnose and treat the problem.
Top Foods to Fight Inflammation

Hylan G-F 20 Drug Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2019 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.