Drug Interactions With Glucosamine and Chondroitin

Diabetes medications, anticoagulant or antiplatelet drugs, acetaminophen, and certain chemotherapy drugs may cause glucosamine and chondroitin drug interactions. These interactions are potentially serious and could lead to reduced effectiveness of the medicines, increased blood sugar, or increased risk of bleeding.

Glucosamine and Chondroitin Supplements

An Introduction to Interactions With Glucosamine and Chondroitin

Glucosamine and chondroitin supplements can potentially interact with several medicines. Some of these medicines that may lead to glucosamine and chondroitin drug interactions include:

Acetaminophen (Tylenol^®)
Certain chemotherapy drugs, such as:

Etoposide (Toposar^®, VePesid^®)
Teniposide (Vumon^®)
Doxorubicin (Adriamycin^®, Doxil^®)

Diabetes medications
Medications that "thin" the blood (anticoagulant and antiplatelet drugs), such as:

Aspirin (Bayer^® and others)
Cilostazol (Pletal^®)
Clopidogrel (Plavix^®)
Dipyridamole (Persantine^®)
Eptifibatide (Integrilin^®)
Heparin or heparin-like products, including dalteparin (Fragmin^®), enoxaparin (Lovenox^®), or tinzaparin (Innohep^®)
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:

Celecoxib (Celebrex^®)

Diclofenac (Cataflam^®, Voltaren^®)

Etodolac (Lodine^®)

Ibuprofen (Motrin^®, Advil^®)

Indomethacin (Indocin^®)

Ketoprofen (Orudis^®)

Ketorolac (Toradol^®)

Meloxicam (Mobic^®)

Naproxen (Naprosyn^®) or naproxen sodium (Aleve^®, Anaprox^®, Naprelan^®)

Nabumetone (Relafen^®)

Oxaprozin (Daypro^®)

Ticlopidine (Ticlid^®)
Tirofiban (Aggrastat^®)
Warfarin (Coumadin^®, Jantoven^®).

(Drug Interactions With Glucosamine and Chondroitin Continued: Page 2)