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What Is Febuxostat Used For?

How Does It Work?

Febuxostat lowers uric acid levels by inhibiting xanthine oxidase, an enzyme responsible for producing uric acid in the body. By inhibiting xanthine oxidase, febuxostat slows down the rate at which the body produces uric acid.
Febuxostat is approved for treating gout. It works well for preventing gout attacks, although it is not very effective for treating a gout attack that is already occurring (in fact, it can temporarily worsen gout, especially at first). For these reasons, febuxostat is usually used along with other gout medications, especially at first. There is no cure for gout, and medications may work better when combined with additional measures, such as a gout diet.

Can Children Use It?

Febuxostat has not been adequately studied in children or adolescents under the age of 18 years old. It is not known if febuxostat is safe or effective for children.

Off-Label Uses for Febuxostat

On occasion, your healthcare provider may recommend febuxostat for something other than gout (this would be known as an "off-label" use). Based on approved or off-label uses of other medications that are similar to febuxostat, it is predicted that off-label uses of febuxostat include the following:
  • Prevention of high uric acid levels due to cancer treatment
  • Prevention of recurrent kidney stones in people with high uric acid levels.
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