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Side Effects of Febuxostat

Common Side Effects of Febuxostat

Febuxostat has been studied extensively in clinical trials. In these studies, the side effects occurring in a group of people taking febuxostat were documented and then compared to the side effects that occurred in a similar group of people taking a placebo (a "sugar pill" that does not contain any active ingredients) or allopurinol (Zyloprim®), a similar gout medication.
Based on these studies, the most common bothersome (but not usually dangerous) side effects of febuxostat included:
  • Nausea -- in up to 1.3 percent of people
  • Joint pain -- up to 1.1 percent.
Liver function abnormalities (such as increased liver enzymes) and rashes were also common, although these side effects could potentially be dangerous (see the following section).


Rare Febuxostat Side Effects

There are other, rare febuxostat side effects that can occur. In clinical studies, these side effects occurred in less than 1 percent of people taking febuxostat. For these side effects, it is difficult to tell whether the side effect is caused by febuxostat or something else.
These rare side effects of febuxostat include, but are not limited to:
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Febuxostat Drug Information

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