Diclofenac Sodium Topical Solution
What Should I Tell My Healthcare Provider?You should talk with your healthcare provider prior to using diclofenac sodium topical solution if you have:
- Heart disease, including congestive heart failure
- High blood pressure (hypertension)
- Liver disease or liver failure
- Kidney disease or kidney failure
- Bleeding problems or are taking blood-thinning medication
- Stomach ulcers, stomach bleeding, or a history of these problems
- Recently had open heart surgery
- Any allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Pennsaid and Pregnancy)
- Breastfeeding (see Pennsaid and Breastfeeding).
Make sure to tell your healthcare provider about all of the medicines you take, including prescription and nonprescription medications, vitamins, and herbal supplements.
(Click Precautions and Warnings With Diclofenac Sodium Topical Solution to learn more, including information on who should not take the drug.)
How Does Diclofenac Sodium Topical Solution Work?
Diclofenac sodium topical solution belongs to a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). Like other NSAIDs, it works by blocking a specific enzyme known as cyclooxygenase (COX), limiting the production of various inflammatory substances in the body.
Because the product works mostly where it is applied, only a small percentage of the medication actually reaches the rest of the body. This helps to lower the drug's exposure to the rest of the body, which may decrease the risk of dangerous side effects.
Diclofenac sodium topical solution contains dimethyl sulfoxide (DMSO), an inactive ingredient that allows for better absorption of the medication through the skin.