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Drug Interactions With Diclofenac Eye Drops

Other eye drops (including steroid eye medications), anticoagulants, and antiplatelet medications can potentially cause drug interactions with diclofenac eye drops. These interactions can increase the risk of side effects (such as bleeding) or cause slow healing. To avoid these negative interactions, you should tell your healthcare provider about any other medications you are using before starting treatment.

An Overview of Diclofenac Eye Drops Interactions

Diclofenac eye drops (Voltaren Ophthalmic®) can potentially interact with several other medications. Even though it is an eye drop, it may be absorbed from the eyes to the rest of the body. Some of the medicines that may lead to drug interactions with diclofenac eye drops include:
  • Medications that "thin" the blood or otherwise increase the risk of bleeding (such as anticoagulant and antiplatelet drugs), such as:
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
  • Steroid eye medications, such as:
    • Dexamethasone (Maxidex®)
    • Difluprednate (Durezol™)
    • Fluorometholone (FML®, Flarex®)
    • Loteprednol (Alrex®, Lotemax®)
    • Medrysone (HMS Liquifilm®)
    • Prednisolone (Omnipred™, Pred Forte®, Pred Mild®)
    • Rimexolone (Vexol®).
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Diclofenac Eye Drop Information

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