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Depo-Testosterone Warnings and Precautions

To help ensure a safe treatment with Depo-Testosterone, make sure your healthcare provider is aware of any other medications you are taking and whether you have any allergies. Other warnings and precautions with Depo-Testosterone involve an increased risk of certain medical problems becoming worse, including infertility, an enlarged prostate, or sleep apnea.

What Should I Tell My Healthcare Provider?

Talk with your healthcare provider prior to using Depo®-Testosterone (testosterone cypionate) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Depo-Testosterone

Some warnings and precautions to be aware of prior to receiving this medicine include the following:
  • Depo-Testosterone can cause or worsen an enlarged prostate. It also appears to increase the risk for prostate cancer. Your healthcare provider should evaluate you for prostate cancer before you start the medication and periodically thereafter.
  • Depo-Testosterone can potentially decrease sperm count, thereby decreasing fertility (although it can also help with certain causes of infertility related to low testosterone). Consult your healthcare provider if you experience difficulty conceiving a child while using this medicine.
  • Androgens can increase the risk for liver problems, including liver cancer. Although these problems have not been reported with Depo-Testosterone, they cannot be completely ruled out.
  • Androgens can cause fluid retention, which can be dangerous for people with liver, heart, or kidney disease.
  • Breast enlargement can occur in men using Depo-Testosterone.
  • This medication can cause or worsen sleep apnea.
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