Precautions and Warnings With Denosumab

To help ensure a safe treatment process with denosumab, make sure your healthcare provider is aware of any other medical conditions you have, such as low blood calcium, severe kidney disease, or underactive parathyroid glands. It is also important to understand the safety precautions with denosumab, such as the warnings of potentially serious infections and possible problems with your jaw.

What Should I Tell My Healthcare Provider Before Taking Denosumab?

You should talk with your healthcare provider prior to receiving injections of denosumab (Prolia™) if you have:
 
  • Low blood calcium (hypocalcemia)
  • Underactive parathyroid glands (hypoparathyroidism)
  • Had thyroid surgery or parathyroid surgery in the past
  • A digestive problem that causes poor absorption of vitamins and minerals
  • Had part of your intestines surgically removed
  • Severe kidney disease (and/or are on dialysis)
  • Any immune-suppressing condition, such as HIV, AIDS, or cancer
  • Any allergies, including allergies to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding
  • Planning a dental procedure.
     
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
Precautions and Warnings With Denosumab Article Continues on Next Page >
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
 
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